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KMID : 0378019710140010121
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New Medical Journal
1971 Volume.14 No. 1 p.121 ~ p.125
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Clinical Observation of Bactrim^(®) in Urinary Tract Infections
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朱槿源/Choo, Kun Weon
禹榮男/朴鍾哲/Woo, Young Nam/Park, Jong Chul
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Abstract
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The efficacy of Bactrim in the treatment of urinary tract infections was evaluated in the Department of Urology, Seoul National University Hospital during the period from July to October, 1970.
Bactrim was administered to 75 cases of urinary tract infection caused by:
Neisseria gonorrheae, 29 cases; Coliform bacilli, 2 cases; Escherichia coli, 23 cases; Enterococci, 2 csaes; Pseudomonas Group, 8 cases; Gram negative bacilli, 3 cases and Proteus Group, 4 cases; Others, 4 cases.
Success was assessed by clinical improvement and significant decrease or disappearance of bacteriuria,and the following result was obtained. Mild side reaction was observed in 6 cases out of 75 cases.
Neisseria gonorrheae 93.1% Coliform bacilli 100%
Escherichia coli 91.1% Enterococci 50%
Pseudomonas Group 25.0% Gram negative bacilli 100%
Proteus Group 100.0% Others 25%
Overall effectiveness of Bactrim was 81.3% of acute and chronic urinary tract infections.
Bactrim was the most sensitive agent for bacteria in this study and the sensitivities were Bactrim 80
%; Kanamycin 60%; Chloramphenicol 55%; Neomycin 48.3%; Penicillin 36.7%; Leucomycin 30%;
Rizynomycine 28.2%; Terramycin 26.7%, Streptomycin 21.7%.
It is disclosed that Bactrim is an effective drug for urinary tract infection.
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